β-Elemene

Product Description of β-Elemene

Tulip-Scented Anti-Tumor Natural Product

β-Elemene is a volatile sesquiterpene natural product, extracted and isolated from the traditional Chinese medicine ginger plant, characterized by a tulip fragrance.

This unique tulip scent gives β-Elemene a distinctive aroma, making it desirable as a unique spice.

Beyond its use as a spice, β-Elemene is recognized in China as an anti-tumor drug with independent intellectual property rights.

Significant Anti-Cancer Effects

Research indicates that β-Elemene exhibits strong anti-tumor activity, has a broad spectrum of action, can cross the blood-brain barrier, and exhibits minimal toxic side effects.

β-Elemene has been shown to potentially reverse the resistance of other anti-cancer drugs.

 As a primary anti-cancer agent, β-Elemene demonstrates significant inhibitory effects on various cancer cells, including liver, lung, brain tumors, nasopharyngeal, esophageal, gastric, cervical, ovarian, leukemia, breast, bladder cancers, and bone metastases.

Industrial Production Challenges

Studies on the synthesis of β-Elemene in China are relatively scarce.

The low natural yield of β-Elemene struggles to meet market demands, and plant-extracted Elemene typically includes a mixture of β, γ, δ-Elemene.

Chemical synthesis allows for the isolated production of β-Elemene, but this method's use of highly toxic substances like sodium cyanide limits its commercial viability.

Hesheng Technology's Efficient β-Elemene Synthesis System

Hesheng Technology has developed an efficient synthesis system for β-Elemene within Saccharomyces cerevisiae.

The company employs high-throughput automation technology to screen for the synthase of Gemmarene A, a precursor in the synthesis of β-Elemene.

Following this, β-Elemene is obtained through a simple in vitro rearrangement process, enhancing the efficiency of its production.

Application of β-Elemene

• Aromatherapy with fragrances

• Pharmaceutical Applications